Knockdown of TRIM8 Protects HK-2 Cells Against Hypoxia/Reoxygenation-Induced Injury by Inhibiting Oxidative Stress-Mediated Apoptosis and Pyroptosis via PI3K/Akt Signal Pathway.
Bang-Hua ZhangHao LiuYan YuanXiao-Dong WengYang DuHui ChenZhi-Yuan ChenLei WangXiu-Heng LiuPublished in: Drug design, development and therapy (2021)
Knockdown of TRIM8 can alleviate H/R-induced oxidative stress by triggering the PI3K/AKT pathway, thus attenuating pyropyosis and apoptosis in vitro.