Impaired monocyte-derived dendritic cell phenotype in prostate cancer patients: A phenotypic comparison with healthy donors.
Parisa BakhshiMaryam NourizadehLaleh SharifiMohammad R NowrooziMonireh MohsenzadeganMohammad M FarajollahiPublished in: Cancer reports (Hoboken, N.J.) (2024)
The limited success of DC vaccines could be attributed to impaired phenotypic characteristics. These observations suggest that suboptimal characteristics of Mo-DCs generated from cancer patient blood samples might contribute to the limited success of DC vaccines. Consequently, this study underscores the need for alternative strategies to enhance the features of Mo-DCs for more effective cancer immunotherapies.
Keyphrases
- dendritic cells
- prostate cancer
- papillary thyroid
- end stage renal disease
- squamous cell
- ejection fraction
- regulatory t cells
- chronic kidney disease
- newly diagnosed
- immune response
- peritoneal dialysis
- case report
- prognostic factors
- squamous cell carcinoma
- childhood cancer
- patient reported outcomes
- peripheral blood
- patient reported