Pharmacological interventions for preventing anthracycline-induced clinical and subclinical cardiotoxicity: A network meta-analysis of metastatic breast cancer.

Khojasteh GhasemiGolnaz VaseghiMarjan Mansourian

Published in: Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners (2020)

Our data suggested that angiotensin-converting enzyme inhibitors and dexrazoxane plus epirubicin were the most effective interventions for preventing cardiotoxicity and CHF. However, ACEIs plus doxorubicin was the best treatment for preventing LVEF reduction.

Keyphrases

angiotensin converting enzyme
metastatic breast cancer
angiotensin ii
physical activity
high glucose
drug delivery
diabetic rats
electronic health record
oxidative stress
machine learning
endothelial cells
artificial intelligence
replacement therapy