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Specific Plasma MicroRNA Signatures in Predicting and Confirming Crohn's Disease Recurrence: Role and Pathogenic Implications.

María José HerreroElena CerrilloDavid HervásMarisa IborraEsteban Sáez-GonzálezJavier FormentLuis TortosaPilar NosJose GadeaBelén Beltrán
Published in: Clinical and translational gastroenterology (2021)
Different plasma miRNA signatures identify patients at high POR risk, which could help optimize patient outcomes. We developed nomograms to facilitate the clinical use of these results. The identified miRNAs participate in apoptosis, autophagy, proinflammatory immunological T-cell clusters, and reactive oxygen species metabolism.
Keyphrases
  • reactive oxygen species
  • endoplasmic reticulum stress
  • cell death
  • oxidative stress
  • genome wide
  • cell cycle arrest
  • signaling pathway
  • free survival
  • dna methylation
  • cell proliferation