RFX6 facilitates aerobic glycolysis-mediated growth and metastasis of hepatocellular carcinoma through targeting PGAM1.

Zhiyu QiuChenwei WangPinzhu HuangYichuan YuanYunxing ShiZhu LinZhenkun HuangDinglan ZuoJiliang QiuWei HeJingxian ShenYi NiuYunfei YuanBin-Kui Li

Published in: Clinical and translational medicine (2023)

RFX6 acted as a novel driver for HCC development by promoting aerobic glycolysis, disclosing the potential of the RFX6-PGAM1 axis for therapeutic targeting.

Keyphrases

cancer therapy
high intensity
risk assessment
human health
drug delivery