A Phenome-Wide Mendelian Randomization Study of Pancreatic Cancer Using Summary Genetic Data.

Ryan J LangdonRebecca C RichmondGibran HemaniJie ZhengKaitlin H Wade Robert Carreras-TorresMattias JohanssonPaul BrennanRobyn E WoottonMarcus R MunafoGeorge Davey SmithCaroline L ReltonEmma E Vincent Richard M MartinPhilip Haycock

Published in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology (2019)

For pancreatic cancer, MR-PheWAS can augment existing risk factor knowledge and generate novel hypotheses to investigate.

Keyphrases

risk factors
healthcare
genome wide
electronic health record
magnetic resonance
dna methylation
machine learning
deep learning