Autism spectrum disorders in extremely preterm infants and placental pathology findings: a matched case-control study.

Imran Nazir MirStormi P WhiteL Steven BrownRoy HeyneCharles R RosenfeldLina F Chalak

Published in: Pediatric research (2020)

PT infants with ASD have a 2-fold greater incidence of multiple placental pathologies. This is the first study to report an association between the complexity of histologic placental lesions and later risk of ASD in infant born extremely PT (i.e., ≤28 weeks GA). This study reiterates the importance of examining placental pathologic lesions, since placental evidence of antenatal insults correlates with postnatal morbidities and mortality in PT infants.

Keyphrases

autism spectrum disorder
preterm infants
low birth weight
pregnant women
risk factors
intellectual disability
attention deficit hyperactivity disorder
cardiovascular disease
gestational age
radiation therapy
coronary artery disease