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Favorable Activity and Safety Profile of Memory-Enriched CD19-Targeted Chimeric Antigen Receptor T Cell Therapy in Adults with high-risk Relapsed/Refractory ALL.

Ibrahim AldossSamer K KhaledXiuli WangJoycelynne PalmerYan WangJamie R WagnerMary C ClarkJennifer SimpsonJinny PaulVibhuti VyasSheng-Hsuan ChienAnthony S SteinVinod A PullarkatAmandeep SalhotraMonzr M Al MalkiSandra H ThomasL Elizabeth Elizabeth BuddeGuido MarcucciChristine E BrownStephen J Forman
Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2022)
Tn/mem-derived CD19-CAR T cells were safe and active, including in Philadelphia-like ALL and EMD.
Keyphrases
  • acute lymphoblastic leukemia
  • acute myeloid leukemia
  • working memory
  • diffuse large b cell lymphoma
  • hodgkin lymphoma
  • cancer therapy
  • stem cells
  • drug delivery
  • mesenchymal stem cells