This study successfully established a method for simultaneously detecting colistin sulfate and tigecycline plasma concentrations. The method was simple, rapid, and highly sensitive and could be applied for therapeutic medication monitoring.
Keyphrases
- liquid chromatography tandem mass spectrometry
- simultaneous determination
- acinetobacter baumannii
- klebsiella pneumoniae
- multidrug resistant
- drug resistant
- pseudomonas aeruginosa
- escherichia coli
- solid phase extraction
- high performance liquid chromatography
- tandem mass spectrometry
- ms ms
- ultra high performance liquid chromatography
- liquid chromatography
- gram negative
- healthcare
- molecularly imprinted
- cystic fibrosis
- high resolution
- mass spectrometry
- living cells
- emergency department
- single molecule
- gas chromatography
- sensitive detection