Classic and 11-oxygenated androgens in serum and saliva across adulthood: a cross-sectional study analyzing the impact of age, body mass index, and diurnal and menstrual cycle variation.

Lina SchifferPunith KempegowdaAlice J SitchJoanne E AdawayFozia ShaheenAndreas Ladefoged EbbehøjSumitabh SinghMalcom P McTaggartMichael W O'ReillyAlessandro PreteJames M HawleyBrian G KeevilIrina BancosAngela E TaylorWiebeke Arlt

Published in: European journal of endocrinology (2023)

Classic androgens decrease while active 11-oxygenated androgens increase with increasing BMI, pointing toward the importance of adipose tissue mass for the activation of 11-oxygenated androgens. Classic but not 11-oxygenated androgens decline with age.

Keyphrases

adipose tissue
body mass index
physical activity
insulin resistance
type diabetes
high fat diet
risk factors