Evidence for the contribution of COMT gene Val158/108Met polymorphism (rs4680) to working memory training-related prefrontal plasticity.

Wan ZhaoLing HuangYang LiQiumei ZhangXiongying ChenWenjin FuBoqi DuXiaoxiang DengFeng JiYu-Tao XiangChuanyue WangXiaohong LiQi DongChuansheng ChenSusanne M JaeggiJun Li

Published in: Brain and behavior (2020)

This study provided evidence for the neural effect of a visual-spatial span training and suggested that genetic factors such as the COMT Val158/108Met polymorphism may have to be considered in future studies of such training.

Keyphrases

working memory
virtual reality
transcranial direct current stimulation
genome wide
tyrosine kinase
attention deficit hyperactivity disorder
copy number
gene expression
functional connectivity
dna methylation
transcription factor
genome wide analysis