Gut flora metagenomic analysis coupled with metabolic and deep immune profiling in chronic kidney disease.
I-Wen WuLun-Ching ChangYi-Lun WuHuang-Yu YangYuh-Ching TwuPo-Yu TsaiSkyler PaulusRhian ResnickWen-Hung ChungChih-Wei YangWen-Ping HsiehShih-Chi SuPublished in: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association (2024)
Overall, our multi-omics integration revealed several signatures of systems-level gut microbiome in robust associations with host-microbe co-metabolites and renal function, which may be of etiological and diagnostic implications in CKD.