The effect of acute and chronic formaldehyde exposure on learning and memory in male and female rats.

Didem Dönmez Aydin Oğuz Taşkınalp Enis Uluçam Hakan Karadağ Gülnur Kızılay Özfidan Ruhan Deniz Topuz Onur Ersoy

Published in: The International journal of neuroscience (2023)

Exposure to intraperitoneal formaldehyde does not impair learning and memory in acute and chronic periods and has no effect on depression or anxiety. After acute exposure, apoptosis was observed in the hippocampal CA1 and CA3 regions in males. When the cognitive test results were examined, no differences were found between the experimental and control groups. There was also no significant difference between males and females.

Keyphrases

liver failure
drug induced
respiratory failure
aortic dissection
room temperature
oxidative stress
sleep quality
endoplasmic reticulum stress
cell death
cell cycle arrest
cell proliferation
physical activity
ionic liquid