Comprehensive Genetic Analysis of 128 Candidate Genes in a Cohort With Idiopathic, Severe, or Familial Osteoporosis.

Manuela G M Rocha-BrazMonica M FrançaAdriana M FernandesAntonio Marcondes LerarioEvelin A ZanardoLucas Santos de Santana Leslie Domenici KulikowskiRegina M MartinBerenice Bilharinho de Mendonca Bruno Ferraz-de-Souza

Published in: Journal of the Endocrine Society (2020)

While we hope that continuing efforts to identify genetic predisposition to OP will lead to improved and personalized care in the future, the likelihood of identifying actionable pathogenic variants in intriguing cases of idiopathic or familial osteoporosis is seemingly low.

Keyphrases

early onset
postmenopausal women
bone mineral density
copy number
quality improvement
healthcare
palliative care
genome wide
current status
body composition
pain management
dna methylation
medical education