Adaptive sample size determination for the development of clinical prediction models.
Evangelia ChristodoulouMaarten van SmedenMichael EdlingerDirk TimmermanMaria WanitschekEwout W SteyerbergBen Van CalsterPublished in: Diagnostic and prognostic research (2021)
Adaptive sample size determination can be a useful supplement to fixed a priori sample size calculations, because it allows to tailor the sample size to the specific prediction modeling context in a dynamic fashion.