Efficacy and safety of antidepressant augmentation of continued antipsychotic treatment in patients with schizophrenia.

B GallingJ A VernonA K PagsbergA WadhwaE GrudnikoffA J SeidmanM Tsoy-PodoseninM PoyurovskyJ M KaneChristoph U Correll

Published in: Acta psychiatrica Scandinavica (2019)

For schizophrenia patients on stable antipsychotic treatment, adjunctive antidepressants are effective for total and particularly negative symptom reduction. However, effects are small-to-medium, differ across antidepressants, and negative symptom improvement seems restricted to the augmentation of FGAs.

Keyphrases

major depressive disorder
bipolar disorder
end stage renal disease
newly diagnosed
patient reported
peritoneal dialysis