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Targeting GPC2 on Intraocular and CNS Metastatic Retinoblastomas with Local and Systemic Delivery of CAR T Cells.

Guillem Pascual-PastoBrendan McIntyreAnna Maria GiudiceFatemeh AlikaramiAmanda MorrisseyStephanie MatlagaTed J HofmannVictor BurgueñoKyra HarveyDaniel MartinezAmish C ShahJessica B FosterJennifer PogorilerRalph C EagleAngel Montero CarcabosoCarol L ShieldsAnn-Marie LeaheyKristopher R Bosse
Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2024)
GPC2-directed CAR T cells are effective against intraocular and CNS metastatic retinoblastomas.
Keyphrases
  • squamous cell carcinoma
  • small cell lung cancer
  • blood brain barrier
  • cataract surgery
  • cancer therapy
  • drug induced