Immortalized erythroid cells as a novel frontier for in vitro blood production: current approaches and potential clinical application.

Christian Felice CervelleraChiara MazziottaGiulia Di MauroMaria Rosa IaquintaElisa MazzoniElena TorreggianiMauro TognonFernanda Martini John Charles Rotondo

Published in: Stem cell research & therapy (2023)

In our review, we provide an overview of the most recent erythroid cell immortalization approaches, while also describing and discussing related advancements of establishing immortalized erythroid cell lines.

Keyphrases

induced apoptosis
single cell
cell cycle arrest
cell therapy
stem cells
endoplasmic reticulum stress
cell proliferation
bone marrow
mesenchymal stem cells
human health
drug induced