The digital expression profile of BMP7, CDKN2C, HIST1H3G, and PKMYT1 genes improves high-grade cervical lesion detection in liquid-based cytology.
Rhafaela Lima CausinLuciane Sussuchi da SilvaLeticia Ferro LealJúlio César Possati-ResendeAdriane Feijó EvangelistaGraziela Macedo MatsushitaCristovam Scapulatempo-NetoJosé Humberto Tavares Guerreiro FregnaniMarco Antônio de OliveiraLaura W MusselwhiteMárcia Maria Chiquitelli MarquesRui Manuel Vieira ReisPublished in: Cancer cytopathology (2023)
A gene expression profile that may be helpful in the identification of patients with CIN2+ was identified. This approach could be used together with currently used LBC in a clinical setting, allowing the identification of patients with high risk of CIN2+.