Clinical evidence of autonomic dysfunction due to atrial fibrillation: implications for rhythm control strategy.
Varun MalikDouglas J McKitrickDennis H LauPrashanthan SandersLeonard F ArnoldaPublished in: Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing (2019)
This study provides novel clinical evidence of autonomic dysfunction in PAF patients. Successful PVI results in partial recovery of the cardiac reflex. Therefore, not only does autonomic disturbance predispose to AF but it is also a consequence of AF; potentially contributing to disease progression. This could help explain the dictum "AF begets AF."
Keyphrases
- atrial fibrillation
- heart rate variability
- heart rate
- oral anticoagulants
- catheter ablation
- left atrial
- left atrial appendage
- end stage renal disease
- direct oral anticoagulants
- heart failure
- ejection fraction
- oxidative stress
- chronic kidney disease
- newly diagnosed
- percutaneous coronary intervention
- prognostic factors
- peritoneal dialysis
- coronary artery disease
- mitral valve