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Vericiguat suppresses ventricular tachyarrhythmias inducibility in a rabbit myocardial infarction model.

Chun-Chieh WangHui-Ling LeeHung-Ta WoHao-Tien LiuMing-Shien WenChung-Chuan Chou
Published in: PloS one (2024)
In the MI rabbit model, vericiguat therapy demonstrates anti-ventricular arrhythmia effects. The vericiguat therapy reduces ventricular ectopic beats, inhibiting the initiation of ventricular arrhythmias. Furthermore, the therapy successfully suppresses cardiac alternans, preventing conduction block and, consequently, the formation of reentry circuits.
Keyphrases
  • left ventricular
  • heart failure
  • catheter ablation
  • signaling pathway