Sodium-glucose cotransporter-2 inhibitors for type 2 diabetes mellitus in adults: An overview of 46 systematic reviews.
Gustavo A AugustoNicolle CassolaPatrícia M DualibHumberto SaconatoTamara MelnikPublished in: Diabetes, obesity & metabolism (2021)
Our results showed that SGLT2 inhibitors have beneficial effects in relation to renal and cardiovascular outcomes (except for stroke), HbA1c and weight. Further studies are needed to assess urinary infections and amputation risk.
Keyphrases
- systematic review
- atrial fibrillation
- body mass index
- physical activity
- lower limb
- glycemic control
- weight gain
- type diabetes
- cardiovascular disease
- metabolic syndrome
- case control
- cardiovascular risk factors
- meta analyses
- skeletal muscle
- peripheral artery disease
- blood brain barrier
- insulin resistance
- cerebral ischemia
- subarachnoid hemorrhage