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Comprehensive Integration of Multiple Single-Cell Transcriptomic Data Sets Defines Distinct Cell Populations and Their Phenotypic Changes in Murine Atherosclerosis.

Vinod ScariaMatthew D WorssamAlbert J PedrozaAlex R DalalHaizea AlemanyHyun-Jung KimRamendra KunduMichael P FischbeinPaul ChengRobert C WirkaThomas Quertermous
Published in: Arteriosclerosis, thrombosis, and vascular biology (2023)
Taken together, these analyses resolve a number of outstanding issues related to differing results reported with vascular disease single-cell RNA sequencing studies, and significantly extend our understanding of the role of resident vascular cells in anatomy and disease.
Keyphrases
  • single cell
  • rna seq
  • high throughput
  • induced apoptosis
  • cell cycle arrest
  • type diabetes
  • patient safety
  • electronic health record
  • quality improvement
  • bone marrow
  • big data
  • cell therapy
  • genetic diversity