DMAP-promoted oxidative functionalization of α-amino ketones via oxygen delivery from water/alcohols.

Ying-Wei WangXiao-Nan LiuJia ZhengJian SuQi-Jun LiXian-Rong CaiQiang Wang Xing-Yong Liang

Published in: Chemical communications (Cambridge, England) (2024)

This paper shows a novel oxidative functionalization of α-amino ketones to yield the corresponding α-ketoamides and α-acylimidates. The reaction proceeds via oxygen delivery from water/alcohols in conjunction with an electron acceptor and 4-dimethylaminopyridine (DMAP). Mechanistic study indicates that DMAP exhibits a dual function of nucleophilic catalysis and proton abstraction.

Keyphrases

electron transfer
solar cells
energy transfer
quantum dots
visible light