Polymorphisms in the CIITA -168A/G (rs3087456) and CIITA +1614G/C (rs4774) may influence severity in multiple sclerosis patients.
Valéria Coelho Santa Rita PereiraFabrícia Lima Fontes-DantasEduardo Ribeiro ParadelaFabíola Rachid MalfetanoSimone de Souza Batista ScherpenhuijzenLetícia Fêzer MansurRonir Raggio LuizAndré Peres De OliveiraJoão Gabriel Dib FarinhasÂngelo MaiolinoSoniza Vieira Alves-LeonPublished in: Arquivos de neuro-psiquiatria (2020)
These data suggest that CIITA -168AA, CIITA +1614GG and CIITA +1614 GC polymorphisms may be associated with a better MS clinical course. This knowledge may be useful for a better understanding of MS and its therapeutic management.