One-pot C-N/C-C bond formation and oxidation of donor-acceptor cyclopropanes with tetrahydroisoquinolines: access to benzo-fused indolizines.

Pallab Karjee Bijoy Debnath Santu Mandal Sharajit Saha Tharmalingam Punniyamurthy

Published in: Chemical communications (Cambridge, England) (2024)

One-pot C-N/C-C bond formation of donor-acceptor cyclopropanes (DACs) with tetrahydroisoquinolines (THIQs) has been achieved to furnish benzo-fused indolizines. These reactions involve a MgI 2 -catalyzed ring opening of DACs and oxidative annulation using Mn(OAc) 3 ·2H 2 O. The substrate scope and functional group diversity are the important practical features.

Keyphrases

room temperature
transition metal
solar cells
energy transfer
hydrogen peroxide
electron transfer
nitric oxide
structural basis