Serum testosterone, sex hormone-binding globulin and sex-specific risk of incident type 2 diabetes in a retrospective primary care cohort.

Michael W O'ReillyMarija GlisicBalachandran KumarendranAnuradhaa SubramanianKonstantinos N ManolopoulosAbd A TahraniDeepi KeerthyTaulant MukaKonstantinos A ToulisWasim HanifG Neil ThomasOscar H FrancoWiebke ArltKrishnarajah Nirantharakumar

Published in: Clinical endocrinology (2018)

In this longitudinal study, we found sexually dimorphic associations between serum testosterone and risk of incident T2DM. Androgen deficiency and excess should be considered important risk factors for diabetes in men and women, respectively.

Keyphrases

type diabetes
cardiovascular disease
primary care
glycemic control
replacement therapy
smoking cessation
insulin resistance
adipose tissue