Chronic rhinosinusitis with nasal polyps does not harbor KRAS, BRAF, and EGFR mutations.

Tamara da Silva VieiraLetícia Martins GuimarãesMarina Gonçalves DinizBianca Gomes-FernandesWilma Terezinha Anselmo-LimaEdwin TamashiroLuciana Bastos-RodriguesLuiz De MarcoRicardo Santiago GomezFabiana Cardoso Pereira ValeraCarolina Cavaliéri Gomes

Published in: Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology (2022)

This finding suggests that mutations in these genes are not a frequent event in CRSwNP, and, if they occur, they might represent marginal events at best.

Keyphrases

chronic rhinosinusitis
small cell lung cancer
wild type
epidermal growth factor receptor
tyrosine kinase
genome wide
gene expression
metastatic colorectal cancer
bioinformatics analysis