Automated enumeration and phenotypic characterization of CTCs and tdEVs in patients with metastatic castration resistant prostate cancer.

Steffi OeyenVincent LiégeoisBram De LaereAndy BuysMichiel StrijbosPiet DirixPaul MeijndersPeter VermeulenSteven Van LaereLuc Dirix

Published in: Prostate cancer and prostatic diseases (2020)

Automated CTC counts are a reliable substitute for reviewer-based enumeration, as they are equally informative for prognosis assessment in patients with mCRPC. Beyond enumeration, we demonstrated the added value of studying CTC phenotypic diversity for patient prognostication, warranting future investigation.

Keyphrases

circulating tumor cells
deep learning
machine learning
high throughput
circulating tumor
case report
current status
peripheral blood
single cell
cell free