Triple fixed-dose combination empagliflozin, linagliptin, and metformin for patients with type 2 diabetes.
Ildiko LingvayNadine BeetzRegina SennewaldAnnette Schuler-MetzJulia BertulisChristina LoleyBenjamin LangCaroline LippertJisoo LeeLinda Shapiro ManningDerek TeradaPublished in: Postgraduate medicine (2020)
The evaluated doses of empagliflozin/linagliptin/metformin XR FDC tablets were bioequivalent to the corresponding free combinations. Based on these two bioequivalence studies and existing phase 3 data, the FDA has recently approved this triple FDC to improve glycemic control in adults with T2D.