Hyperbaric oxygen should be used for carbon monoxide poisoning.
Kinjal SethuramanStephen R ThomPublished in: British journal of clinical pharmacology (2022)
This short review addresses the mechanisms of injury mediated by carbon monoxide (CO) and current information on efficacy of hyperbaric oxygen therapy (HBOT). Recent clinical series involving large, country-wide databases and prospective randomized trials are summarized. We conclude that there is an abundance of basic science and preclinical and clinical research supporting the use of HBOT for acute CO poisoning. With appropriate consideration for pathology and therapeutic mechanisms, HBOT at a dose of 2.5-3.0 atm absolute is a necessary treatment for this toxidrome.
Keyphrases
- liver failure
- public health
- dna damage
- respiratory failure
- dna damage response
- stem cells
- health information
- antibiotic resistance genes
- big data
- hepatitis b virus
- social media
- wastewater treatment
- bone marrow
- microbial community
- extracorporeal membrane oxygenation
- mechanical ventilation
- acute respiratory distress syndrome