Postoperative chemoradiotherapy versus radiotherapy alone for elderly cervical cancer patients with positive margins, lymph nodes, or parametrial invasion.
Taylor R CushmanWaqar HaqueHari MenonAbdullah M SheneamerE Brian ButlerBin S TehVivek VermaPublished in: Journal of gynecologic oncology (2019)
In the largest such study to date, older women with postoperative risk factor(s) receiving RT alone experienced similar survival as those undergoing CRT. Although causation is not implied, careful patient selection is paramount to balance treatment-related toxicity risks with theoretical outcome benefits.
Keyphrases
- lymph node
- patients undergoing
- locally advanced
- community dwelling
- middle aged
- risk factors
- rectal cancer
- early stage
- oxidative stress
- case report
- physical activity
- radiation induced
- squamous cell carcinoma
- neoadjuvant chemotherapy
- cell migration
- human health
- cardiac resynchronization therapy
- left ventricular
- drug induced
- replacement therapy
- climate change