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Impact of rs11024102 PLEKHA7, rs3753841 COL11A1 single nucleotide polymorphisms, and serum levels of oxidative stress markers on the risk of primary angle-closure glaucoma in Egyptians.

Marwa AswaHazem HelmyShahira NoweirSomaia IsmailAlShaimaa M TahaAzza Atef
Published in: Journal, genetic engineering & biotechnology (2022)
Both rs11024102 and rs3753841 could not be considered as potential gene-dependent risk factors for PACG pathogenesis in Egyptians. On the other hand, serum levels of MDA, AOPP, and PC might be considered risk factors for PACG. Moreover, MDA and PC could serve as good predictors for the elevation of the IOP in PACG disease.
Keyphrases
  • oxidative stress
  • breast cancer cells
  • high resolution
  • copy number
  • gene expression
  • cell cycle arrest
  • dna methylation
  • climate change
  • signaling pathway
  • endoplasmic reticulum stress
  • optic nerve