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Contribution of sleep disturbances to fatigue in multiple sclerosis: a prospective study using clinical and polysomnographic parameters.

Gianna Carla RiccitelliGiulio DisantoRosaria SaccoDavide SparasciLeonardo SaccoAnna CastelnovoSilvia MianoMauro ManconiClaudio GobbiChiara Zecca
Published in: European journal of neurology (2021)
Multiple sclerosis patients with a diagnosis of RLS had significantly higher global fatigue scores compared to those without RLS. Future studies should investigate whether medical treatment of RLS can ameliorate fatigue.
Keyphrases
  • multiple sclerosis
  • sleep quality
  • white matter
  • healthcare
  • depressive symptoms
  • physical activity
  • case control
  • smoking cessation