Loss of ADAM15 Exacerbates Transition to Decompensated Myocardial Hypertrophy and Dilation Through Activation of the Calcineurin Pathway.
Preetinder K AujlaMei HuBridgette HartleyJoshua W KranrodAnissa ViveirosTolga KilicCaroline A OwenGavin Y OuditJohn M SeubertOlivier JulienZamaneh KassiriPublished in: Hypertension (Dallas, Tex. : 1979) (2022)
This is the first report demonstrating that ADAM15 can suppress hypertrophy through regulating the integrin-laminin interaction and the calcineurin pathway.
Keyphrases