Gefitinib and Afatinib Show Potential Efficacy for Fanconi Anemia-Related Head and Neck Cancer.
Helena MontanuyÁgueda Martínez-BarriocanalJose A CasadoLlorenç RovirosaMaria José RamírezRocío NietoCarlos Carrascoso-RubioPau RieraAlan GonzálezEnrique LermaAdriana LasaJordi Carreras-PuigvertThomas HelledayJuan A BuerenDiego ArangoJordi MinguillónJordi SurrallésPublished in: Clinical cancer research : an official journal of the American Association for Cancer Research (2020)
Our data present a complete preclinical analysis and promising therapeutic line of the first FDA/EMA-approved anticancer drugs exerting cancer-specific toxicity for HNSCC in patients with Fanconi anemia.
Keyphrases
- chronic kidney disease
- iron deficiency
- epidermal growth factor receptor
- papillary thyroid
- small cell lung cancer
- electronic health record
- squamous cell
- big data
- cell therapy
- stem cells
- squamous cell carcinoma
- advanced non small cell lung cancer
- climate change
- human health
- lymph node metastasis
- data analysis
- mesenchymal stem cells
- artificial intelligence
- deep learning
- childhood cancer