Maternal and paternal exercise regulate offspring metabolic health and beta cell phenotype.
Jia ZhengAna Barbara Alves-WagnerKristin I StanfordNoah B PrinceKawai SoJoram D MulErcument DiriceMichael F HirshmanRohit N KulkarniLaurie J GoodyearPublished in: BMJ open diabetes research & care (2021)
Maternal and paternal exercise have additive effects to improve glucose tolerance in offspring as they age, accompanied by changes in the offspring endocrine pancreas. These findings have important implications for the prevention and treatment of type 2 diabetes.
Keyphrases
- high fat diet
- type diabetes
- high intensity
- birth weight
- healthcare
- physical activity
- pregnancy outcomes
- insulin resistance
- public health
- resistance training
- single cell
- mental health
- adipose tissue
- cardiovascular disease
- health information
- metabolic syndrome
- pregnant women
- stem cells
- skeletal muscle
- body mass index
- weight gain
- replacement therapy
- human health