Dysfunctional voiding behavior and impaired muscle contractility in a rat model of detrusor underactivity.
Eric J GonzalezMichael R OdomJohanna L HannanWarren M GrillPublished in: Neurourology and urodynamics (2021)
Impaired cholinergic and purinergic signaling in the bladder may contribute to poor voiding function in OP rats. In addition, increased urethral activity may engage a guarding reflex to augment continence and exacerbate incomplete emptying.