Screening for clinically relevant drug-drug interactions between direct oral anticoagulants and antineoplastic agents: a pharmacovigilance approach.

Cong Bang TruongLori HornsbyBrent I FoxChiahung ChouJingyi ZhengJingjing Qian

Published in: Journal of thrombosis and thrombolysis (2023)

No signal of DDIs between DOACs and antineoplastic agents was detected, except for DOAC-neratinib. Most DDIs between DOACs and antineoplastic agents may not be clinically relevant. The DDIs between DOACs and neratinib should be further examined in future research.

Keyphrases

direct oral anticoagulants
venous thromboembolism
atrial fibrillation
adverse drug
positive breast cancer
emergency department
electronic health record