Relationship between impaired BMP signalling and clinical risk factors at early-stage vascular injury in the preterm infant.
Motaharehsadat HeydarianPrajakta OakXin ZhangNona KamgariAlida KindtMarkus KoschligTina PritzkeErika Gonzalez-RodriguezKai M FörsterRory E MortyFriederike HäfnerChristoph HübenerAndreas W FlemmerAli Oender YildirimDeepti SudheendraXuefei TianAgnese PetreraHolger KirstenPeter AhnertNick MorrellTushar J DesaiJennifer SucreEdda SpiekerkoetterAnne HilgendorffPublished in: Thorax (2022)
We identified impaired BMP signalling as a hallmark of early vascular disease in the injured neonatal lung while outlining its promising potential as a future biomarker or therapeutic target in this growing, high-risk patient population.