The genetics and epidemiology of N- and O-immunoglobulin A glycomics.

Alessia ViscontiNiccolò RossiAlbert BondtAgnes Hipgrave EderveenGaurav TharejaCarolien A M KoelemanNisha StephanAnna HalamaHannah J Lomax-BrowneMatthew C PickeringXu-Jie ZhouManfred WuhrerKarsten SuhreMario Falchi

Published in: Genome medicine (2024)

Our study delineates the genetic landscape of IgA glycosylation and provides novel potential functional links with the aetiology of complex immune diseases, including genetic factors involved in IgA nephropathy risk.

Keyphrases

genome wide
copy number
risk factors
single cell
gene expression
risk assessment
climate change