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The genetics and epidemiology of N- and O-immunoglobulin A glycomics.

Alessia ViscontiNiccolò RossiAlbert BondtAgnes Hipgrave EderveenGaurav TharejaCarolien A M KoelemanNisha StephanAnna HalamaHannah J Lomax-BrowneMatthew C PickeringXu-Jie ZhouManfred WuhrerKarsten SuhreMario Falchi
Published in: Genome medicine (2024)
Our study delineates the genetic landscape of IgA glycosylation and provides novel potential functional links with the aetiology of complex immune diseases, including genetic factors involved in IgA nephropathy risk.
Keyphrases
  • genome wide
  • copy number
  • risk factors
  • single cell
  • gene expression
  • risk assessment
  • climate change