Combination of human umbilical cord mesenchymal stem (stromal) cell transplantation with IFN-γ treatment synergistically improves the clinical outcomes of patients with rheumatoid arthritis.
Xiao HeYi YangMengwei YaoLei YangLuoquan AoXueting HuZhan LiXiaofeng WuYan TanWei XingWei GuoJoseph A BellantiSong Guo ZhengXiang XuPublished in: Annals of the rheumatic diseases (2020)
The results of this study show that IFN-γ is a key factor in determining the efficacy of MSCT in the treatment of RA, and that an MSC plus IFN-γ combination therapeutic strategy can greatly improve the clinical efficacy of MSC-based therapy in RA patients.