Antioxidants as a Potential Target against Inflammation and Oxidative Stress in Attention-Deficit/Hyperactivity Disorder.
Lourdes Alvarez-ArellanoNadia González-GarcíaMarcela Salazar-GarcíaJuan Carlos CoronaPublished in: Antioxidants (Basel, Switzerland) (2020)
Psychostimulants and non-psychostimulants are the medications prescribed for the treatment of attention-deficit/hyperactivity disorder (ADHD). However, several adverse results have been linked with an increased risk of substance use and side effects. The pathophysiology of ADHD is not completely known, although it has been associated with an increase in inflammation and oxidative stress. This review presents an overview of findings following antioxidant treatment for ADHD and describes the potential amelioration of inflammation and oxidative stress using antioxidants that might have a future as multi-target adjuvant therapy in ADHD. The use of antioxidants against inflammation and oxidative conditions is an emerging field in the management of several neurodegenerative and neuropsychiatric disorders. Thus, antioxidants could be promising as an adjuvant ADHD therapy.
Keyphrases
- attention deficit hyperactivity disorder
- oxidative stress
- autism spectrum disorder
- diabetic rats
- ischemia reperfusion injury
- dna damage
- induced apoptosis
- working memory
- emergency department
- risk assessment
- signaling pathway
- mesenchymal stem cells
- smoking cessation
- replacement therapy
- anti inflammatory
- electronic health record