Production and characterization of virus-free, CRISPR-CAR T cells capable of inducing solid tumor regression.
Katherine P MuellerNicole J PiscopoMatthew H ForsbergLouise A SaraspeAmritava DasBrittany RussellMadeline SmerchanskyDan CappabiancaLei ShiKeerthana ShankarLauren SarkoNamita KhajanchiNina La Vonne DenneApoorva RamamurthyAdeela AliCicera R LazzarottoShengdar Q TsaiChristian M CapitiniKrishanu SahaPublished in: Journal for immunotherapy of cancer (2022)
-targeted CAR, which could inform manufacturing of CAR T cells to treat cancers, including solid tumors.