Hypoxia-Induced HIF-1α Expression Promotes Neurogenic Bladder Fibrosis via EMT and Pyroptosis.
Qi LiYifan HongJing ChenXiazhu ZhouXiaomao TianYihang YuLianju ShenChunlan LongMiao CaiShengde WuGuanghui WeiPublished in: Cells (2022)
EMT and pyroptosis were involved in the development of SCI-induced bladder fibrosis via the HIF-1α pathway. Inhibition of the HIF-1α pathway may serve as a potential target to alleviate bladder fibrosis caused by SCI.