Growth differentiation factor 7 autocrine signaling promotes hepatic progenitor cell expansion in liver fibrosis.
De-Fu KongApostolos MourtzinosJanette HeegsmaHans BlokzijlVincent E de MeijerKlaas Nico FaberPublished in: Stem cell research & therapy (2023)
Collectively, this study reveals a role of GDF7 in liver fibrosis and suggests a potential pro-regenerative function that can be utilized for amelioration of hepatic fibrosis caused by chronic liver disease.