RARα and RARγ reciprocally control K5+ progenitor cell expansion in developing salivary glands.

Kara A DeSantisAdam R StabellDanielle C SpitzerKevin J O'KeefeDeirdre A NelsonMelinda Larsen

Published in: Organogenesis (2017)

RARα and RARγ reciprocally control K5+ progenitor cell proliferation and distribution in the developing submandibular salivary epithelium in a cell cycle-dependent manner while regulating lumenization independently of keratinizing differentiation.

Keyphrases

cell cycle
cell proliferation
signaling pathway