A child with Klinefelter syndrome and both IgE-mediated food allergy and low proportion of naive Treg.

Rachel FrederickPeter VuillerminMimi L K TangAnne-Louise PonsonbyElise WebsterRichard SafferyFiona Colliernull null

Published in: Clinical case reports (2019)

This case suggests a possible association between Klinefelter Syndrome and decreased regulatory T cells (Treg) cells, relating to an increased risk of allergic and autoimmune disorders in these patients. The immune phenotyping of the circulating FOXP3+ naive Treg populations in KS patients may help to indicate this predisposition.

Keyphrases

regulatory t cells
end stage renal disease
ejection fraction
chronic kidney disease
prognostic factors
multiple sclerosis
induced apoptosis
dendritic cells
hiv infected
oxidative stress
immune response
endoplasmic reticulum stress
patient reported
atopic dermatitis