2.5-Year changes of connectivity dynamism are relevant for physical and cognitive deterioration in multiple sclerosis.

Maria Assunta RoccaGiulia D'AmorePaola ValsasinaNicolò TedoneAlessandro Meani Massimo Filippi

Published in: Multiple sclerosis (Houndmills, Basingstoke, England) (2024)

At 2.5-year follow-up, default-mode network TVFC reductions were found in worsening MS. Moreover, reduced deep gray matter TVFC characterized physically worsened patients, whereas precuneus involvement characterized cognitively worsened MS patients.

Keyphrases

multiple sclerosis
end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
mass spectrometry
prognostic factors
mental health
functional connectivity
cognitive decline