A 6-year prospective clinical cohort study on the bidirectional association between frailty and depressive disorder.
Richard C Oude VoshaarMenelaos DimitriadisRob H S vandenBrinkIvan AprahamianMarcus Kiiti BorgesRadboud M MarijnissenEmiel O HoogendijkDidi RhebergenHans W JeuringPublished in: International journal of geriatric psychiatry (2021)
The sum score of depression rating scales is likely confounded by frailty. Depressive disorder, according to DSM-IV criteria, is associated with accelerated biological ageing. This argues for the development of multidisciplinary geriatric care models incorporating frailty to improve the overall outcome of late-life depression.